The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue

Bones are metabolically active organs. Their reconstruction is crucial for the proper functioning of the skeletal system during bone growth and remodeling, fracture healing, and maintaining calcium–phosphorus homeostasis. The bone metabolism and tissue properties are influenced by trace elements tha...

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Detalles Bibliográficos
Autores principales: Ciosek, Żaneta, Kot, Karolina, Kosik-Bogacka, Danuta, Łanocha-Arendarczyk, Natalia, Rotter, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066206/
https://www.ncbi.nlm.nih.gov/pubmed/33800689
http://dx.doi.org/10.3390/biom11040506
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author Ciosek, Żaneta
Kot, Karolina
Kosik-Bogacka, Danuta
Łanocha-Arendarczyk, Natalia
Rotter, Iwona
author_facet Ciosek, Żaneta
Kot, Karolina
Kosik-Bogacka, Danuta
Łanocha-Arendarczyk, Natalia
Rotter, Iwona
author_sort Ciosek, Żaneta
collection PubMed
description Bones are metabolically active organs. Their reconstruction is crucial for the proper functioning of the skeletal system during bone growth and remodeling, fracture healing, and maintaining calcium–phosphorus homeostasis. The bone metabolism and tissue properties are influenced by trace elements that may act either indirectly through the regulation of macromineral metabolism, or directly by affecting osteoblast and osteoclast proliferation or activity, or through becoming part of the bone mineral matrix. This study analyzes the skeletal impact of macroelements (calcium, magnesium, phosphorus), microelements (fluorine), and heavy metals (lead), and discusses the concentration of each of these elements in the various bone tissues.
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spelling pubmed-80662062021-04-25 The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue Ciosek, Żaneta Kot, Karolina Kosik-Bogacka, Danuta Łanocha-Arendarczyk, Natalia Rotter, Iwona Biomolecules Review Bones are metabolically active organs. Their reconstruction is crucial for the proper functioning of the skeletal system during bone growth and remodeling, fracture healing, and maintaining calcium–phosphorus homeostasis. The bone metabolism and tissue properties are influenced by trace elements that may act either indirectly through the regulation of macromineral metabolism, or directly by affecting osteoblast and osteoclast proliferation or activity, or through becoming part of the bone mineral matrix. This study analyzes the skeletal impact of macroelements (calcium, magnesium, phosphorus), microelements (fluorine), and heavy metals (lead), and discusses the concentration of each of these elements in the various bone tissues. MDPI 2021-03-28 /pmc/articles/PMC8066206/ /pubmed/33800689 http://dx.doi.org/10.3390/biom11040506 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review
Ciosek, Żaneta
Kot, Karolina
Kosik-Bogacka, Danuta
Łanocha-Arendarczyk, Natalia
Rotter, Iwona
The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue
title The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue
title_full The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue
title_fullStr The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue
title_full_unstemmed The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue
title_short The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue
title_sort effects of calcium, magnesium, phosphorus, fluoride, and lead on bone tissue
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066206/
https://www.ncbi.nlm.nih.gov/pubmed/33800689
http://dx.doi.org/10.3390/biom11040506
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