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Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project

Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project gathered ST...

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Autores principales: Bennett, Julia C., Hetrich, Marissa K., Garcia Quesada, Maria, Sinkevitch, Jenna N., Deloria Knoll, Maria, Feikin, Daniel R., Zeger, Scott L., Kagucia, Eunice W., Cohen, Adam L., Ampofo, Krow, Brandileone, Maria-Cristina C., Bruden, Dana, Camilli, Romina, Castilla, Jesús, Chan, Guanhao, Cook, Heather, Cornick, Jennifer E., Dagan, Ron, Dalby, Tine, Danis, Kostas, de Miguel, Sara, De Wals, Philippe, Desmet, Stefanie, Georgakopoulou, Theano, Gilkison, Charlotte, Grgic-Vitek, Marta, Hammitt, Laura L., Hilty, Markus, Ho, Pak-Leung, Jayasinghe, Sanjay, Kellner, James D., Kleynhans, Jackie, Knol, Mirjam J., Kozakova, Jana, Kristinsson, Karl G., Ladhani, Shamez N., MacDonald, Laura, Mackenzie, Grant A., Mad’arová, Lucia, McGeer, Allison, Mereckiene, Jolita, Morfeldt, Eva, Mungun, Tuya, Muñoz-Almagro, Carmen, Nuorti, J. Pekka, Paragi, Metka, Pilishvili, Tamara, Puentes, Rodrigo, Saha, Samir K., Sahu Khan, Aalisha, Savrasova, Larisa, Scott, J. Anthony, Skoczyńska, Anna, Suga, Shigeru, van der Linden, Mark, Verani, Jennifer R., von Gottberg, Anne, Winje, Brita A., Yildirim, Inci, Zerouali, Khalid, Hayford, Kyla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066231/
https://www.ncbi.nlm.nih.gov/pubmed/33801760
http://dx.doi.org/10.3390/microorganisms9040696
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author Bennett, Julia C.
Hetrich, Marissa K.
Garcia Quesada, Maria
Sinkevitch, Jenna N.
Deloria Knoll, Maria
Feikin, Daniel R.
Zeger, Scott L.
Kagucia, Eunice W.
Cohen, Adam L.
Ampofo, Krow
Brandileone, Maria-Cristina C.
Bruden, Dana
Camilli, Romina
Castilla, Jesús
Chan, Guanhao
Cook, Heather
Cornick, Jennifer E.
Dagan, Ron
Dalby, Tine
Danis, Kostas
de Miguel, Sara
De Wals, Philippe
Desmet, Stefanie
Georgakopoulou, Theano
Gilkison, Charlotte
Grgic-Vitek, Marta
Hammitt, Laura L.
Hilty, Markus
Ho, Pak-Leung
Jayasinghe, Sanjay
Kellner, James D.
Kleynhans, Jackie
Knol, Mirjam J.
Kozakova, Jana
Kristinsson, Karl G.
Ladhani, Shamez N.
MacDonald, Laura
Mackenzie, Grant A.
Mad’arová, Lucia
McGeer, Allison
Mereckiene, Jolita
Morfeldt, Eva
Mungun, Tuya
Muñoz-Almagro, Carmen
Nuorti, J. Pekka
Paragi, Metka
Pilishvili, Tamara
Puentes, Rodrigo
Saha, Samir K.
Sahu Khan, Aalisha
Savrasova, Larisa
Scott, J. Anthony
Skoczyńska, Anna
Suga, Shigeru
van der Linden, Mark
Verani, Jennifer R.
von Gottberg, Anne
Winje, Brita A.
Yildirim, Inci
Zerouali, Khalid
Hayford, Kyla
author_facet Bennett, Julia C.
Hetrich, Marissa K.
Garcia Quesada, Maria
Sinkevitch, Jenna N.
Deloria Knoll, Maria
Feikin, Daniel R.
Zeger, Scott L.
Kagucia, Eunice W.
Cohen, Adam L.
Ampofo, Krow
Brandileone, Maria-Cristina C.
Bruden, Dana
Camilli, Romina
Castilla, Jesús
Chan, Guanhao
Cook, Heather
Cornick, Jennifer E.
Dagan, Ron
Dalby, Tine
Danis, Kostas
de Miguel, Sara
De Wals, Philippe
Desmet, Stefanie
Georgakopoulou, Theano
Gilkison, Charlotte
Grgic-Vitek, Marta
Hammitt, Laura L.
Hilty, Markus
Ho, Pak-Leung
Jayasinghe, Sanjay
Kellner, James D.
Kleynhans, Jackie
Knol, Mirjam J.
Kozakova, Jana
Kristinsson, Karl G.
Ladhani, Shamez N.
MacDonald, Laura
Mackenzie, Grant A.
Mad’arová, Lucia
McGeer, Allison
Mereckiene, Jolita
Morfeldt, Eva
Mungun, Tuya
Muñoz-Almagro, Carmen
Nuorti, J. Pekka
Paragi, Metka
Pilishvili, Tamara
Puentes, Rodrigo
Saha, Samir K.
Sahu Khan, Aalisha
Savrasova, Larisa
Scott, J. Anthony
Skoczyńska, Anna
Suga, Shigeru
van der Linden, Mark
Verani, Jennifer R.
von Gottberg, Anne
Winje, Brita A.
Yildirim, Inci
Zerouali, Khalid
Hayford, Kyla
author_sort Bennett, Julia C.
collection PubMed
description Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project gathered ST1 IPD surveillance data from sites globally and aimed to estimate PCV10/13 impact on ST1 IPD incidence. We estimated ST1 IPD incidence rate ratios (IRRs) comparing the pre-PCV10/13 period to each post-PCV10/13 year by site using a Bayesian multi-level, mixed-effects Poisson regression and all-site IRRs using a linear mixed-effects regression (N = 45 sites). Following PCV10/13 introduction, the incidence rate (IR) of ST1 IPD declined among all ages. After six years of PCV10/13 use, the all-site IRR was 0.05 (95% credibility interval 0.04–0.06) for all ages, 0.05 (0.04–0.05) for <5 years of age, 0.08 (0.06–0.09) for 5–17 years, 0.06 (0.05–0.08) for 18–49 years, 0.06 (0.05–0.07) for 50–64 years, and 0.05 (0.04–0.06) for ≥65 years. PCV10/13 use in infant immunization programs was followed by a 95% reduction in ST1 IPD in all ages after approximately 6 years. Limited data availability from the highest ST1 disease burden countries using a 3 + 0 schedule constrains generalizability and data from these settings are needed.
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spelling pubmed-80662312021-04-25 Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project Bennett, Julia C. Hetrich, Marissa K. Garcia Quesada, Maria Sinkevitch, Jenna N. Deloria Knoll, Maria Feikin, Daniel R. Zeger, Scott L. Kagucia, Eunice W. Cohen, Adam L. Ampofo, Krow Brandileone, Maria-Cristina C. Bruden, Dana Camilli, Romina Castilla, Jesús Chan, Guanhao Cook, Heather Cornick, Jennifer E. Dagan, Ron Dalby, Tine Danis, Kostas de Miguel, Sara De Wals, Philippe Desmet, Stefanie Georgakopoulou, Theano Gilkison, Charlotte Grgic-Vitek, Marta Hammitt, Laura L. Hilty, Markus Ho, Pak-Leung Jayasinghe, Sanjay Kellner, James D. Kleynhans, Jackie Knol, Mirjam J. Kozakova, Jana Kristinsson, Karl G. Ladhani, Shamez N. MacDonald, Laura Mackenzie, Grant A. Mad’arová, Lucia McGeer, Allison Mereckiene, Jolita Morfeldt, Eva Mungun, Tuya Muñoz-Almagro, Carmen Nuorti, J. Pekka Paragi, Metka Pilishvili, Tamara Puentes, Rodrigo Saha, Samir K. Sahu Khan, Aalisha Savrasova, Larisa Scott, J. Anthony Skoczyńska, Anna Suga, Shigeru van der Linden, Mark Verani, Jennifer R. von Gottberg, Anne Winje, Brita A. Yildirim, Inci Zerouali, Khalid Hayford, Kyla Microorganisms Article Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project gathered ST1 IPD surveillance data from sites globally and aimed to estimate PCV10/13 impact on ST1 IPD incidence. We estimated ST1 IPD incidence rate ratios (IRRs) comparing the pre-PCV10/13 period to each post-PCV10/13 year by site using a Bayesian multi-level, mixed-effects Poisson regression and all-site IRRs using a linear mixed-effects regression (N = 45 sites). Following PCV10/13 introduction, the incidence rate (IR) of ST1 IPD declined among all ages. After six years of PCV10/13 use, the all-site IRR was 0.05 (95% credibility interval 0.04–0.06) for all ages, 0.05 (0.04–0.05) for <5 years of age, 0.08 (0.06–0.09) for 5–17 years, 0.06 (0.05–0.08) for 18–49 years, 0.06 (0.05–0.07) for 50–64 years, and 0.05 (0.04–0.06) for ≥65 years. PCV10/13 use in infant immunization programs was followed by a 95% reduction in ST1 IPD in all ages after approximately 6 years. Limited data availability from the highest ST1 disease burden countries using a 3 + 0 schedule constrains generalizability and data from these settings are needed. MDPI 2021-03-27 /pmc/articles/PMC8066231/ /pubmed/33801760 http://dx.doi.org/10.3390/microorganisms9040696 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Bennett, Julia C.
Hetrich, Marissa K.
Garcia Quesada, Maria
Sinkevitch, Jenna N.
Deloria Knoll, Maria
Feikin, Daniel R.
Zeger, Scott L.
Kagucia, Eunice W.
Cohen, Adam L.
Ampofo, Krow
Brandileone, Maria-Cristina C.
Bruden, Dana
Camilli, Romina
Castilla, Jesús
Chan, Guanhao
Cook, Heather
Cornick, Jennifer E.
Dagan, Ron
Dalby, Tine
Danis, Kostas
de Miguel, Sara
De Wals, Philippe
Desmet, Stefanie
Georgakopoulou, Theano
Gilkison, Charlotte
Grgic-Vitek, Marta
Hammitt, Laura L.
Hilty, Markus
Ho, Pak-Leung
Jayasinghe, Sanjay
Kellner, James D.
Kleynhans, Jackie
Knol, Mirjam J.
Kozakova, Jana
Kristinsson, Karl G.
Ladhani, Shamez N.
MacDonald, Laura
Mackenzie, Grant A.
Mad’arová, Lucia
McGeer, Allison
Mereckiene, Jolita
Morfeldt, Eva
Mungun, Tuya
Muñoz-Almagro, Carmen
Nuorti, J. Pekka
Paragi, Metka
Pilishvili, Tamara
Puentes, Rodrigo
Saha, Samir K.
Sahu Khan, Aalisha
Savrasova, Larisa
Scott, J. Anthony
Skoczyńska, Anna
Suga, Shigeru
van der Linden, Mark
Verani, Jennifer R.
von Gottberg, Anne
Winje, Brita A.
Yildirim, Inci
Zerouali, Khalid
Hayford, Kyla
Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project
title Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project
title_full Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project
title_fullStr Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project
title_full_unstemmed Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project
title_short Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project
title_sort changes in invasive pneumococcal disease caused by streptococcus pneumoniae serotype 1 following introduction of pcv10 and pcv13: findings from the pserenade project
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066231/
https://www.ncbi.nlm.nih.gov/pubmed/33801760
http://dx.doi.org/10.3390/microorganisms9040696
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