Cargando…

Immunogenicity and Neutralizing Activity Comparison of SARS-CoV-2 Spike Full-Length and Subunit Domain Proteins in Young Adult and Old-Aged Mice

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be expanding the pandemic disease across the globe. Although SARS-CoV-2 vaccines were rapidly developed and approved for emergency use of vaccination in humans, supply and production difficulties are slowing down the global va...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ki-Hye, Bhatnagar, Noopur, Jeeva, Subbiah, Oh, Judy, Park, Bo Ryoung, Shin, Chong Hyun, Wang, Bao-Zhong, Kang, Sang-Moo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066235/ https://www.ncbi.nlm.nih.gov/pubmed/33805473 http://dx.doi.org/10.3390/vaccines9040316

Ejemplares similares

A chimeric thermostable M2e and H3 stalk-based universal influenza A virus vaccine
por: Subbiah, Jeeva, et al.
Publicado: (2022)

Universal protection against influenza viruses by multi-subtype neuraminidase and M2 ectodomain virus-like particle
por: Kim, Ki-Hye, et al.
Publicado: (2022)

Adjuvant Effects of a New Saponin Analog VSA-1 on Enhancing Homologous and Heterosubtypic Protection by Influenza Virus Vaccination
por: Bhatnagar, Noopur, et al.
Publicado: (2022)

Heterologous Prime-Boost Vaccination with Inactivated Influenza Viruses Induces More Effective Cross-Protection than Homologous Repeat Vaccination
por: Bhatnagar, Noopur, et al.
Publicado: (2023)

Thermostable H1 hemagglutinin stem with M2e epitopes provides broad cross-protection against group1 and 2 influenza A viruses
por: Subbbiah, Jeeva, et al.
Publicado: (2022)

Broad cross protection by recombinant live attenuated influenza H3N2 seasonal virus expressing conserved M2 extracellular domain in a chimeric hemagglutinin
por: Park, Bo Ryoung, et al.
Publicado: (2021)

An Update on mRNA-Based Viral Vaccines
por: Jeeva, Subbiah, et al.
Publicado: (2021)

Towards Goals to Refine Prophylactic and Therapeutic Strategies Against COVID-19 Linked to Aging and Metabolic Syndrome
por: Shin, Chong-Hyun, et al.
Publicado: (2021)

Hemagglutinin virus-like particles incorporated with membrane-bound cytokine adjuvants provide protection against homologous and heterologous influenza virus challenge in aged mice
por: Park, Bo Ryoung, et al.
Publicado: (2023)

Recombinant Live Attenuated Influenza Virus Expressing Conserved G-Protein Domain in a Chimeric Hemagglutinin Molecule Induces G-Specific Antibodies and Confers Protection against Respiratory Syncytial Virus
por: Jung, Yu-Jin, et al.
Publicado: (2020)

Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines
por: Du, Lanying, et al.
Publicado: (2016)

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit
por: Hurlburt, Nicholas K., et al.
Publicado: (2022)

PCR Amplification and Sequencing Analysis of Full-Length Turkey Coronavirus Spike Gene
por: Chen, Yi-Ning, et al.
Publicado: (2015)

Generation of the transgenic potato expressing full-length spike protein of infectious bronchitis virus
por: Zhou, Ji-Yong, et al.
Publicado: (2004)

Immunogenicity of a receptor-binding domain of SARS coronavirus spike protein in mice: Implications for a subunit vaccine
por: Zakhartchouk, Alexander N., et al.
Publicado: (2007)

Recombinant subunits of SARS‐CoV‐2 spike protein as vaccine candidates to elicit neutralizing antibodies
por: Noorabad Ghahroodi, Faezeh, et al.
Publicado: (2022)

Cellular and Humoral Immunogenicity of a Candidate DNA Vaccine Expressing SARS-CoV-2 Spike Subunit 1
por: Alluhaybi, Khalid A., et al.
Publicado: (2021)

Full-length HIV-1 immunogens induce greater T lymphocyte responses to conserved epitopes than conserved-region-only HIV-1 immunogens in monkeys
por: Stephenson, KE, et al.
Publicado: (2012)

Increased Immunogenicity of Full-Length Protein Antigens through Sortase-Mediated Coupling on the PapMV Vaccine Platform
por: Laliberté-Gagné, Marie-Ève, et al.
Publicado: (2019)

Enhancement of immunogenicity and neutralizing responses against SARS-CoV-2 spike protein using the Fc fusion fragment
por: Ehteshaminia, Yahya, et al.
Publicado: (2023)

Cooh-Terminal Truncated Alpha(1S) Subunits Conduct Current Better than Full-Length Dihydropyridine Receptors
por: Morrill, James A., et al.
Publicado: (2000)

P19-41. Full-length IMC expressing Renilla luciferase for neutralization assay using PBMC
por: Chenine, A, et al.
Publicado: (2009)

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate
por: Bangaru, Sandhya, et al.
Publicado: (2020)

SARS-CoV-2 full length spike protein for COVID-19 vaccine development and diagnostic testing
por: Richardson, Crystal, et al.
Publicado: (2021)

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate
por: Bangaru, Sandhya, et al.
Publicado: (2020)

Immunogenicity and Efficacy Evaluation of Subunit Astrovirus Vaccines
por: Bidokhti, Mehdi R.M., et al.
Publicado: (2019)

The Case for S2: The Potential Benefits of the S2 Subunit of the SARS-CoV-2 Spike Protein as an Immunogen in Fighting the COVID-19 Pandemic
por: Shah, Priyanka, et al.
Publicado: (2021)

A Spike Protein-Based Subunit SARS-CoV-2 Vaccine for Pets: Safety, Immunogenicity, and Protective Efficacy in Juvenile Cats
por: Tabynov, Kairat, et al.
Publicado: (2022)

Mind the Gap: New Full-Length Sequences of Blastocystis Subtypes Generated via Oxford Nanopore Minion Sequencing Allow for Comparisons between Full-Length and Partial Sequences of the Small Subunit of the Ribosomal RNA Gene
por: Maloney, Jenny G., et al.
Publicado: (2021)

Analysis of Simian Endogenous Retrovirus (SERV) Full-Length Proviruses in Old World Monkey Genomes
por: van der Kuyl, Antoinette C.
Publicado: (2022)

Quantitative comparison of the efficiency of antibodies against S1 and S2 subunit of SARS coronavirus spike protein in virus neutralization and blocking of receptor binding: Implications for the functional roles of S2 subunit
por: Zeng, Fanya, et al.
Publicado: (2006)

Comparative Immunogenicities of Full-Length Plasmodium falciparum Merozoite Surface Protein 3 and a 24-Kilodalton N-Terminal Fragment
por: Imam, Marvam, et al.
Publicado: (2012)

α-Hemolysin-Aided Oligomerization of the Spike Protein RBD Resulted in Improved Immunogenicity and Neutralization Against SARS-CoV-2 Variants
por: Zou, Jintao, et al.
Publicado: (2021)

Conformational states of the full-length glucagon receptor
por: Yang, Linlin, et al.
Publicado: (2015)

Immunogenicity and safety of subunit influenza vaccines in pregnant women
por: Kostinov, Mikhail P., et al.
Publicado: (2018)

Recombinant Zika Virus Subunits Are Immunogenic and Efficacious in Mice
por: To, Albert, et al.
Publicado: (2018)

A viral subunit immunogen for porcine transmissible gastroenteritis
por: Gough, Patricia M., et al.
Publicado: (1983)

Nanoparticles in influenza subunit vaccine development: Immunogenicity enhancement
por: Khalaj‐Hedayati, Atin, et al.
Publicado: (2019)

Immunogenicity of the spike glycoprotein of Bat SARS-like coronavirus
por: Hou, Yu-xuan, et al.
Publicado: (2010)

Use of Oxford Nanopore MinION to generate full-length sequences of the Blastocystis small subunit (SSU) rRNA gene
por: Maloney, Jenny G., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m7m03o8hhsht34me4i4s75fqhg