A Novel Low-Risk Germline Variant in the SH2 Domain of the SRC Gene Affects Multiple Pathways in Familial Colorectal Cancer

Colorectal cancer (CRC) shows one of the largest proportions of familial cases among different malignancies, but only 5–10% of all CRC cases are linked to mutations in established predisposition genes. Thus, familial CRC constitutes a promising target for the identification of novel, high- to modera...

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Detalles Bibliográficos
Autores principales: Skopelitou, Diamanto, Miao, Beiping, Srivastava, Aayushi, Kumar, Abhishek, Kuświk, Magdalena, Dymerska, Dagmara, Paramasivam, Nagarajan, Schlesner, Matthias, Lubiński, Jan, Hemminki, Kari, Försti, Asta, Bandapalli, Obul Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066297/
https://www.ncbi.nlm.nih.gov/pubmed/33916261
http://dx.doi.org/10.3390/jpm11040262

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