Anticancer Activity of Triazolo-Thiadiazole Derivatives and Inhibition of AKT1 and AKT2 Activation

The fusion of 1,2,4-triazole and 1,3,4-thiadiazole rings results in a class of heterocycles compounds with an extensive range of pharmacological properties. A series of 1,2,4-triazolo[3,4-b]-1,2,4-thiadiazoles was synthesized and tested for its enzyme inhibition potential and anticancer activity. Th...

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Detalles Bibliográficos
Autores principales: Trafalis, Dimitrios T., Sagredou, Sofia, Dalezis, Panayiotis, Voura, Maria, Fountoulaki, Stella, Nikoleousakos, Nikolaos, Almpanakis, Konstantinos, Deligiorgi, Maria V., Sarli, Vasiliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066331/
https://www.ncbi.nlm.nih.gov/pubmed/33916378
http://dx.doi.org/10.3390/pharmaceutics13040493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066331/
https://www.ncbi.nlm.nih.gov/pubmed/33916378
http://dx.doi.org/10.3390/pharmaceutics13040493

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