Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears

Rotator cuff (RC) disease is a common musculoskeletal disorder of the shoulder entailing pain, with reduced functionality and quality of life. The main objective of this study was to present a perspective of the current scientific evidence about personalized, predictive, participatory, precision, an...

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Autores principales: Longo, Umile Giuseppe, Carnevale, Arianna, Massaroni, Carlo, Lo Presti, Daniela, Berton, Alessandra, Candela, Vincenzo, Schena, Emiliano, Denaro, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066336/
https://www.ncbi.nlm.nih.gov/pubmed/33915689
http://dx.doi.org/10.3390/jpm11040255
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author Longo, Umile Giuseppe
Carnevale, Arianna
Massaroni, Carlo
Lo Presti, Daniela
Berton, Alessandra
Candela, Vincenzo
Schena, Emiliano
Denaro, Vincenzo
author_facet Longo, Umile Giuseppe
Carnevale, Arianna
Massaroni, Carlo
Lo Presti, Daniela
Berton, Alessandra
Candela, Vincenzo
Schena, Emiliano
Denaro, Vincenzo
author_sort Longo, Umile Giuseppe
collection PubMed
description Rotator cuff (RC) disease is a common musculoskeletal disorder of the shoulder entailing pain, with reduced functionality and quality of life. The main objective of this study was to present a perspective of the current scientific evidence about personalized, predictive, participatory, precision, and preventive approaches in the management of RC diseases. The personalized, predictive, participatory, precision and preventive (P5) medicine model is an interdisciplinary and multidisciplinary approach that will provide researchers and clinicians with a comprehensive patrimony of knowledge in the management of RC diseases. The ability to define genetic predispositions in conjunction with the evaluation of lifestyle and environmental factors may boost the tailoring of diagnosis and therapy in patients suffering from RC diseases.
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spelling pubmed-80663362021-04-25 Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears Longo, Umile Giuseppe Carnevale, Arianna Massaroni, Carlo Lo Presti, Daniela Berton, Alessandra Candela, Vincenzo Schena, Emiliano Denaro, Vincenzo J Pers Med Perspective Rotator cuff (RC) disease is a common musculoskeletal disorder of the shoulder entailing pain, with reduced functionality and quality of life. The main objective of this study was to present a perspective of the current scientific evidence about personalized, predictive, participatory, precision, and preventive approaches in the management of RC diseases. The personalized, predictive, participatory, precision and preventive (P5) medicine model is an interdisciplinary and multidisciplinary approach that will provide researchers and clinicians with a comprehensive patrimony of knowledge in the management of RC diseases. The ability to define genetic predispositions in conjunction with the evaluation of lifestyle and environmental factors may boost the tailoring of diagnosis and therapy in patients suffering from RC diseases. MDPI 2021-04-01 /pmc/articles/PMC8066336/ /pubmed/33915689 http://dx.doi.org/10.3390/jpm11040255 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Perspective
Longo, Umile Giuseppe
Carnevale, Arianna
Massaroni, Carlo
Lo Presti, Daniela
Berton, Alessandra
Candela, Vincenzo
Schena, Emiliano
Denaro, Vincenzo
Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears
title Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears
title_full Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears
title_fullStr Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears
title_full_unstemmed Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears
title_short Personalized, Predictive, Participatory, Precision, and Preventive (P5) Medicine in Rotator Cuff Tears
title_sort personalized, predictive, participatory, precision, and preventive (p5) medicine in rotator cuff tears
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066336/
https://www.ncbi.nlm.nih.gov/pubmed/33915689
http://dx.doi.org/10.3390/jpm11040255
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