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Lower Density Selection Schemes via Small Universal Hitting Sets with Short Remaining Path Length

Universal hitting sets (UHS) are sets of words that are unavoidable: every long enough sequence is hit by the set (i.e., it contains a word from the set). There is a tight relationship between UHS and minimizer schemes, where minimizer schemes with low density (i.e., efficient schemes) correspond to...

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Detalles Bibliográficos
Autores principales: Zheng, Hongyu, Kingsford, Carl, Marçais, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066347/
https://www.ncbi.nlm.nih.gov/pubmed/33325773
http://dx.doi.org/10.1089/cmb.2020.0432
Descripción
Sumario:Universal hitting sets (UHS) are sets of words that are unavoidable: every long enough sequence is hit by the set (i.e., it contains a word from the set). There is a tight relationship between UHS and minimizer schemes, where minimizer schemes with low density (i.e., efficient schemes) correspond to UHS of small size. Local schemes are a generalization of minimizer schemes that can be used as replacement for minimizer scheme with the possibility of being much more efficient. We establish the link between efficient local schemes and the minimum length of a string that must be hit by a UHS. We give bounds for the remaining path length of the Mykkeltveit UHS. In addition, we create a local scheme with the lowest known density that is only a log factor away from the theoretical lower bound.