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Chondroprotective effect of melatonin and strontium ranelate in animal model of osteoarthritis

PURPOSE: To analyze the action of strontium ranelate (SR) and melatonin in isolation or in association in knees, liver and kidneys of rats Wistar with induced osteoarthritis (OA). METHODS: Thirty male rats were induced to OA through an anterior cruciate ligament transection (ACLT), and treated with...

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Detalles Bibliográficos
Autores principales: Paulino Silva, Kássya Mycaela, de Sousa, Francisco Lucas, Alves, Ana Carolina Barreto, Rocha, Pollyana Alves, da Costa, Hildegard Naara Alves Furtado, Ferreira, Waldilene Rodrigues, Reis, Taianara Sampaio, de Oliveira, Tharcia Kiara Beserra, Cabral Batista, Sandra Rejane, Lapa Neto, Clovis José Cavalcanti, Oliveira, Anne Gabrielle, de Lemos Jordão, Ana Janaina Jeanine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066349/
https://www.ncbi.nlm.nih.gov/pubmed/33912721
http://dx.doi.org/10.1016/j.heliyon.2021.e06760