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Dissecting the Molecular Determinants of GABA(A) Receptors Current Rundown, a Hallmark of Refractory Human Epilepsy

GABA(A) receptors-(Rs) are fundamental for the maintenance of an efficient inhibitory function in the central nervous system (CNS). Their dysfunction is associated with a wide range of CNS disorders, many of which characterized by seizures and epilepsy. Recently, an increased use-dependent desensiti...

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Detalles Bibliográficos
Autores principales: Cifelli, Pierangelo, Di Angelantonio, Silvia, Alfano, Veronica, Morano, Alessandra, De Felice, Eleonora, Aronica, Eleonora, Ruffolo, Gabriele, Palma, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066365/
https://www.ncbi.nlm.nih.gov/pubmed/33808090
http://dx.doi.org/10.3390/brainsci11040441