Transcriptional and Non-Transcriptional Activation, Posttranslational Modifications, and Antiviral Functions of Interferon Regulatory Factor 3 and Viral Antagonism by the SARS-Coronavirus

The immune system defends against invading pathogens through the rapid activation of innate immune signaling pathways. Interferon regulatory factor 3 (IRF3) is a key transcription factor activated in response to virus infection and is largely responsible for establishing an antiviral state in the in...

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Detalles Bibliográficos
Autores principales: Glanz, Anna, Chakravarty, Sukanya, Varghese, Merina, Kottapalli, Anita, Fan, Shumin, Chakravarti, Ritu, Chattopadhyay, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066409/
https://www.ncbi.nlm.nih.gov/pubmed/33805458
http://dx.doi.org/10.3390/v13040575

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