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Identification and mechanistic analysis of an inhibitor of the CorC Mg(2+) transporter

The CorC/CNNM family of Na(+)-dependent Mg(2+) transporters is ubiquitously conserved from bacteria to humans. CorC, the bacterial CorC/CNNM family of proteins, is involved in resistance to antibiotic exposure and in the survival of pathogenic microorganisms in their host environment. The CorC/CNNM...

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Detalles Bibliográficos
Autores principales: Huang, Yichen, Mu, Kaijie, Teng, Xinyu, Zhao, Yimeng, Funato, Yosuke, Miki, Hiroaki, Zhu, Weiliang, Xu, Zhijian, Hattori, Motoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066426/
https://www.ncbi.nlm.nih.gov/pubmed/33912817
http://dx.doi.org/10.1016/j.isci.2021.102370