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Finding associations in a heterogeneous setting: statistical test for aberration enrichment

Most two-group statistical tests find broad patterns such as overall shifts in mean, median, or variance. These tests may not have enough power to detect effects in a small subset of samples, e.g., a drug that works well only on a few patients. We developed a novel statistical test targeting such ef...

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Detalles Bibliográficos
Autores principales: Mezlini, Aziz M., Das, Sudeshna, Goldenberg, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066476/
https://www.ncbi.nlm.nih.gov/pubmed/33892787
http://dx.doi.org/10.1186/s13073-021-00864-4