Bombesin-Tethered Reactive Oxygen Species (ROS)-Responsive Nanoparticles for Monomethyl Auristatin F (MMAF) Delivery

Dolastatin derivatives, represented by monomethylauristatin E (MMAE), have been translated in clinic with a form of antibody–drug conjugate; however, their potential in nanoparticle systems has not been well established due to the potential risk of immature release of extremely high cytotoxic dolast...

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Detalles Bibliográficos
Autores principales: Kim, Jihoon, Kim, Jee Seon, Min, Kyung Hyun, Kim, Young-Hwa, Chen, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066503/
https://www.ncbi.nlm.nih.gov/pubmed/33805342
http://dx.doi.org/10.3390/bioengineering8040043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066503/
https://www.ncbi.nlm.nih.gov/pubmed/33805342
http://dx.doi.org/10.3390/bioengineering8040043

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