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Bombesin-Tethered Reactive Oxygen Species (ROS)-Responsive Nanoparticles for Monomethyl Auristatin F (MMAF) Delivery
Dolastatin derivatives, represented by monomethylauristatin E (MMAE), have been translated in clinic with a form of antibody–drug conjugate; however, their potential in nanoparticle systems has not been well established due to the potential risk of immature release of extremely high cytotoxic dolast...
Autores principales: | Kim, Jihoon, Kim, Jee Seon, Min, Kyung Hyun, Kim, Young-Hwa, Chen, Xiaoyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066503/ https://www.ncbi.nlm.nih.gov/pubmed/33805342 http://dx.doi.org/10.3390/bioengineering8040043 |
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