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Hepatic Stellate Cell Activation and Inactivation in NASH-Fibrosis—Roles as Putative Treatment Targets?

Hepatic fibrosis is the primary predictor of mortality in patients with non-alcoholic steatohepatitis (NASH). In this process, the activated hepatic stellate cells (HSCs) constitute the principal cells responsible for the deposition of a fibrous extracellular matrix, thereby driving the hepatic scar...

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Detalles Bibliográficos
Autores principales: Zisser, Alexandra, Ipsen, David H., Tveden-Nyborg, Pernille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066583/
https://www.ncbi.nlm.nih.gov/pubmed/33807461
http://dx.doi.org/10.3390/biomedicines9040365