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Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania

Breast cancer is the most common cause of mortality due to cancer for women both in Lithuania and worldwide. Chances of survival after diagnosis differ significantly depending on the stage of disease at the time of diagnosis. Extended term periods are required to estimate survival of, e.g., 15–20 ye...

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Autores principales: Skučaitė, Aldona, Puvačiauskienė, Alma, Puišys, Rokas, Šiaulys, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066802/
https://www.ncbi.nlm.nih.gov/pubmed/33915700
http://dx.doi.org/10.3390/healthcare9040383
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author Skučaitė, Aldona
Puvačiauskienė, Alma
Puišys, Rokas
Šiaulys, Jonas
author_facet Skučaitė, Aldona
Puvačiauskienė, Alma
Puišys, Rokas
Šiaulys, Jonas
author_sort Skučaitė, Aldona
collection PubMed
description Breast cancer is the most common cause of mortality due to cancer for women both in Lithuania and worldwide. Chances of survival after diagnosis differ significantly depending on the stage of disease at the time of diagnosis. Extended term periods are required to estimate survival of, e.g., 15–20 years. Moreover, since mortality of the average population changes with time, estimates of survival of cancer patients derived after a long period of observation can become outdated and can be no longer used to estimate survival of patients who were diagnosed later. Therefore, it can be useful to construct analytic functions that describe survival probabilities. Shorter periods of observation can be enough for such construction. We used the data collected by the Lithuanian Cancer Registry for our analysis. We estimated the chances of survival for up to 5 years after patients were diagnosed with breast cancer in Lithuania. Then we found analytic survival functions which best fit the observed data. At the end of this paper, we provided some examples for applications and directions for further research. We used mainly the Kaplan–Meier method for our study.
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spelling pubmed-80668022021-04-25 Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania Skučaitė, Aldona Puvačiauskienė, Alma Puišys, Rokas Šiaulys, Jonas Healthcare (Basel) Article Breast cancer is the most common cause of mortality due to cancer for women both in Lithuania and worldwide. Chances of survival after diagnosis differ significantly depending on the stage of disease at the time of diagnosis. Extended term periods are required to estimate survival of, e.g., 15–20 years. Moreover, since mortality of the average population changes with time, estimates of survival of cancer patients derived after a long period of observation can become outdated and can be no longer used to estimate survival of patients who were diagnosed later. Therefore, it can be useful to construct analytic functions that describe survival probabilities. Shorter periods of observation can be enough for such construction. We used the data collected by the Lithuanian Cancer Registry for our analysis. We estimated the chances of survival for up to 5 years after patients were diagnosed with breast cancer in Lithuania. Then we found analytic survival functions which best fit the observed data. At the end of this paper, we provided some examples for applications and directions for further research. We used mainly the Kaplan–Meier method for our study. MDPI 2021-04-01 /pmc/articles/PMC8066802/ /pubmed/33915700 http://dx.doi.org/10.3390/healthcare9040383 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Skučaitė, Aldona
Puvačiauskienė, Alma
Puišys, Rokas
Šiaulys, Jonas
Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania
title Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania
title_full Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania
title_fullStr Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania
title_full_unstemmed Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania
title_short Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania
title_sort actuarial analysis of survival among breast cancer patients in lithuania
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066802/
https://www.ncbi.nlm.nih.gov/pubmed/33915700
http://dx.doi.org/10.3390/healthcare9040383
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