Cargando…
Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania
Breast cancer is the most common cause of mortality due to cancer for women both in Lithuania and worldwide. Chances of survival after diagnosis differ significantly depending on the stage of disease at the time of diagnosis. Extended term periods are required to estimate survival of, e.g., 15–20 ye...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066802/ https://www.ncbi.nlm.nih.gov/pubmed/33915700 http://dx.doi.org/10.3390/healthcare9040383 |
_version_ | 1783682653192454144 |
---|---|
author | Skučaitė, Aldona Puvačiauskienė, Alma Puišys, Rokas Šiaulys, Jonas |
author_facet | Skučaitė, Aldona Puvačiauskienė, Alma Puišys, Rokas Šiaulys, Jonas |
author_sort | Skučaitė, Aldona |
collection | PubMed |
description | Breast cancer is the most common cause of mortality due to cancer for women both in Lithuania and worldwide. Chances of survival after diagnosis differ significantly depending on the stage of disease at the time of diagnosis. Extended term periods are required to estimate survival of, e.g., 15–20 years. Moreover, since mortality of the average population changes with time, estimates of survival of cancer patients derived after a long period of observation can become outdated and can be no longer used to estimate survival of patients who were diagnosed later. Therefore, it can be useful to construct analytic functions that describe survival probabilities. Shorter periods of observation can be enough for such construction. We used the data collected by the Lithuanian Cancer Registry for our analysis. We estimated the chances of survival for up to 5 years after patients were diagnosed with breast cancer in Lithuania. Then we found analytic survival functions which best fit the observed data. At the end of this paper, we provided some examples for applications and directions for further research. We used mainly the Kaplan–Meier method for our study. |
format | Online Article Text |
id | pubmed-8066802 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80668022021-04-25 Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania Skučaitė, Aldona Puvačiauskienė, Alma Puišys, Rokas Šiaulys, Jonas Healthcare (Basel) Article Breast cancer is the most common cause of mortality due to cancer for women both in Lithuania and worldwide. Chances of survival after diagnosis differ significantly depending on the stage of disease at the time of diagnosis. Extended term periods are required to estimate survival of, e.g., 15–20 years. Moreover, since mortality of the average population changes with time, estimates of survival of cancer patients derived after a long period of observation can become outdated and can be no longer used to estimate survival of patients who were diagnosed later. Therefore, it can be useful to construct analytic functions that describe survival probabilities. Shorter periods of observation can be enough for such construction. We used the data collected by the Lithuanian Cancer Registry for our analysis. We estimated the chances of survival for up to 5 years after patients were diagnosed with breast cancer in Lithuania. Then we found analytic survival functions which best fit the observed data. At the end of this paper, we provided some examples for applications and directions for further research. We used mainly the Kaplan–Meier method for our study. MDPI 2021-04-01 /pmc/articles/PMC8066802/ /pubmed/33915700 http://dx.doi.org/10.3390/healthcare9040383 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Skučaitė, Aldona Puvačiauskienė, Alma Puišys, Rokas Šiaulys, Jonas Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania |
title | Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania |
title_full | Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania |
title_fullStr | Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania |
title_full_unstemmed | Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania |
title_short | Actuarial Analysis of Survival among Breast Cancer Patients in Lithuania |
title_sort | actuarial analysis of survival among breast cancer patients in lithuania |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066802/ https://www.ncbi.nlm.nih.gov/pubmed/33915700 http://dx.doi.org/10.3390/healthcare9040383 |
work_keys_str_mv | AT skucaitealdona actuarialanalysisofsurvivalamongbreastcancerpatientsinlithuania AT puvaciauskienealma actuarialanalysisofsurvivalamongbreastcancerpatientsinlithuania AT puisysrokas actuarialanalysisofsurvivalamongbreastcancerpatientsinlithuania AT siaulysjonas actuarialanalysisofsurvivalamongbreastcancerpatientsinlithuania |