Cargando…
Cell-Based Reporter Release Assay to Determine the Activity of Calcium-Dependent Neurotoxins and Neuroactive Pharmaceuticals
The suitability of a newly developed cell-based functional assay was tested for the detection of the activity of a range of neurotoxins and neuroactive pharmaceuticals which act by stimulation or inhibition of calcium-dependent neurotransmitter release. In this functional assay, a reporter enzyme is...
Autores principales: | Pathe-Neuschäfer-Rube, Andrea, Neuschäfer-Rube, Frank, Püschel, Gerhard P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066854/ https://www.ncbi.nlm.nih.gov/pubmed/33808507 http://dx.doi.org/10.3390/toxins13040247 |
Ejemplares similares
-
Cell-Based Reporter Release Assay to Determine the Potency of Proteolytic Bacterial Neurotoxins
por: Pathe-Neuschäfer-Rube, Andrea, et al.
Publicado: (2018) -
Discrimination of the Activity of Low-Affinity Wild-Type and High-Affinity Mutant Recombinant BoNT/B by a SIMA Cell-Based Reporter Release Assay
por: Neuschäfer-Rube, Frank, et al.
Publicado: (2022) -
LDL-Dependent Regulation of TNFα/PGE(2) Induced COX-2/mPGES-1 Expression in Human Macrophage Cell Lines
por: Neuschäfer-Rube, Frank, et al.
Publicado: (2023) -
The Mammalian INDY Homolog Is Induced by CREB in a Rat Model of Type 2 Diabetes
por: Neuschäfer-Rube, Frank, et al.
Publicado: (2014) -
Radiation-Induced Brain Injury: Age Dependency of Neurocognitive Dysfunction Following Radiotherapy
por: Rübe, Claudia E., et al.
Publicado: (2023)