Cargando…

A high level of lncFGD5-AS1 inhibits epithelial-to-Mesenchymal transition by regulating the miR-196a-5p/SMAD6/BMP axis in gastric Cancer

BACKGROUND: Long non-coding RNA (lncRNA) was a vital factor in the progression and initiation of human cancers. This study found a new lncRNA, FGD5-AS1, which can inhibit EMT process, proliferation, and metastasis in vitro and in vivo. METHODS: qRT-PCR was employed to test the expression of lncFGD5-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Lin, Zhang, Cheng, Wang, Jizhao, Liu, Xu, Qu, Hangying, Zhang, Guangjian, Liang, Ting, Wang, Jiansheng, Zhang, Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066889/ https://www.ncbi.nlm.nih.gov/pubmed/33892661 http://dx.doi.org/10.1186/s12885-021-08192-x

Ejemplares similares

LINC00461 Overexpression Can Induce Docetaxel Resistance in Breast Cancer by Interacting with miR-411-5p
por: Zhang, Cheng, et al.
Publicado: (2020)

Oxidative stress activates NORAD expression by H3K27ac and promotes oxaliplatin resistance in gastric cancer by enhancing autophagy flux via targeting the miR-433-3p
por: Wang, Jizhao, et al.
Publicado: (2021)

Targeting the lncRNA FGD5-AS1/miR-497-5p/PD-L1 Axis Inhibits Malignant Phenotypes in Colon Cancer (CC)
por: Zhang, Lijuan, et al.
Publicado: (2022)

lncRNA FGD5-AS1 promotes breast cancer progression by regulating the hsa-miR-195-5p/NUAK2 axis
por: Fang, Kun, et al.
Publicado: (2021)

LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma
por: Zhang, Nuobei, et al.
Publicado: (2021)

FGD5-AS1 facilitates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting the miR-506-3p/BMP7 axis
por: Li, Jun, et al.
Publicado: (2021)

Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis
por: Monsivais, Diana, et al.
Publicado: (2021)

Targeting EGFR sensitizes 5-Fu-resistant colon cancer cells through modification of the lncRNA-FGD5-AS1-miR-330-3p-Hexokinase 2 axis
por: Gao, Su-Jie, et al.
Publicado: (2021)

Retracted: Targeting the lncRNA FGD5-AS1/miR-497-5p/PD-L1 Axis Inhibits Malignant Phenotypes in Colon Cancer (CC)
por: International, BioMed Research
Publicado: (2023)

lncRNA FGD5-AS1 Regulates Bone Marrow Stem Cell Proliferation and Apoptosis by Affecting miR-296-5p/STAT3 Axis in Steroid-Induced Osteonecrosis of the Femoral Head
por: Wu, Yadi, et al.
Publicado: (2022)

FGD5-AS1 is an oncogenic lncRNA in pancreatic cancer and regulates the Wnt/β-catenin signaling pathway via miR-577
por: Zhang, Wei-Tao, et al.
Publicado: (2022)

CircKIF4A promotes non-small cell lung cancer proliferation and metastasis through MiR-1238/CLDN14 axis
por: Luo, Weimin, et al.
Publicado: (2022)

The role of long non-coding RNA FGD5-AS1 in cancer
por: He, Na, et al.
Publicado: (2022)

FGD5-AS1 Is a Hub lncRNA ceRNA in Hearts With Tetralogy of Fallot Which Regulates Congenital Heart Disease Genes Transcriptionally and Epigenetically
por: Zhang, Xingyu, et al.
Publicado: (2021)

BMP-7 suppresses excessive scar formation by activating the BMP-7/Smad1/5/8 signaling pathway
por: Guo, Jingdong, et al.
Publicado: (2017)

MYC overexpression with its prognostic and clinicopathological significance in breast cancer
por: Qu, Jingkun, et al.
Publicado: (2017)

BMP-SMAD1/5 Signaling Regulates Retinal Vascular Development
por: Benn, Andreas, et al.
Publicado: (2020)

METTL3-induced lncRNA GBAP1 promotes hepatocellular carcinoma progression by activating BMP/SMAD pathway
por: Liu, Runkun, et al.
Publicado: (2023)

Fgd5 identifies hematopoietic stem cells in the murine bone marrow
por: Gazit, Roi, et al.
Publicado: (2014)

lncRNA FGD5-AS1 and miR-130a Can Be Used for Prognosis Analysis of Patients with Chronic Periodontitis
por: Yu, Miao, et al.
Publicado: (2021)

The lncRNA DLGAP1-AS1/miR-149-5p/TGFB2 axis contributes to colorectal cancer progression and 5-FU resistance by regulating smad2 pathway
por: Qu, Linlin, et al.
Publicado: (2021)

LncSNHG1 Promoted CRC Proliferation through the miR-181b-5p/SMAD2 Axis
por: Huang, Qi, et al.
Publicado: (2022)

The lncRNA Rhno1/miR-6979-5p/BMP2 Axis Modulates Osteoblast Differentiation
por: Xiong, Yuan, et al.
Publicado: (2020)

miR-765 inhibits the osteogenic differentiation of human bone marrow mesenchymal stem cells by targeting BMP6 via regulating the BMP6/Smad1/5/9 signaling pathway
por: Wang, Tao, et al.
Publicado: (2020)

LncRNA FGD5-AS1 promotes tumor growth by regulating MCL1 via sponging miR-153-3p in oral cancer
por: Ge, Chao, et al.
Publicado: (2020)

Circular RNA circCRKL inhibits the proliferation of acute myeloid leukemia cells via the miR-196a-5p/miR-196b-5p/p27 axis
por: Liu, Wen, et al.
Publicado: (2021)

Tumor-Derived Exosome FGD5-AS1 Promotes Angiogenesis, Vascular Permeability, and Metastasis in Thyroid Cancer by Targeting the miR-6838-5p/VAV2 Axis
por: Liu, Bo, et al.
Publicado: (2022)

FGD1 Variant Associated With Aarskog–Scott Syndrome
por: Zhu, Yilin, et al.
Publicado: (2022)

miR-196a-5p modulates gastric cancer stem cell characteristics by targeting Smad4
por: Pan, Yunzhi, et al.
Publicado: (2017)

Hic-5 Controls BMP4 Responses in Prostate Cancer Cells through Interacting with Smads 1, 5 and 8
por: Shola, Dorjee T.N., et al.
Publicado: (2011)

BMP2 promotes lung adenocarcinoma metastasis through BMP receptor 2-mediated SMAD1/5 activation
por: Wu, Cheng-Kuei, et al.
Publicado: (2022)

FGD5-AS1 promotes cisplatin resistance of human lung adenocarcinoma cell via the miR-142-5p/PD-L1 axis
por: Zhu, Feng, et al.
Publicado: (2021)

EBF1-mediated up-regulation of lncRNA FGD5-AS1 facilitates osteosarcoma progression by regulating miR-124-3p/G3BP2 axis as a ceRNA
por: Shuang, Ou, et al.
Publicado: (2022)

LncRNAs Predicted to Interfere With the Gene Regulation Activity of miR-637 and miR-196a-5p in GBM
por: Zheng, Jingfang, et al.
Publicado: (2020)

BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease
por: Peng, Wei, et al.
Publicado: (2022)

LncRNA FGD5-AS1 Facilitates the Radioresistance of Breast Cancer Cells by Enhancing MACC1 Expression Through Competitively Sponging miR-497-5p
por: Li, Ji, et al.
Publicado: (2021)

lncRNA FGD5 antisense RNA 1 upregulates RORA to suppress hypoxic injury of human cardiomyocyte cells by inhibiting oxidative stress and apoptosis via miR-195
por: Cai, Xinyong, et al.
Publicado: (2020)

Selective Small Molecule Compounds Increase BMP-2 Responsiveness by Inhibiting Smurf1-mediated Smad1/5 Degradation
por: Cao, Yu, et al.
Publicado: (2014)

Lncrna FGD5-AS1 Aggravates Myocardial Ischemia-Reperfusion Injury by Sponging Mir-129-5p
por: Wei, Peng, et al.
Publicado: (2022)

Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation
por: Liu, Jia, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_rgrb61fuqqjqcs5e1thq442te5