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Adjuvants and Vaccines Used in Allergen-Specific Immunotherapy Induce Neutrophil Extracellular Traps
Aluminum hydroxide (alum) and monophosphoryl-lipid A (MPLA) are conventional adjuvants in vaccines for allergen-specific immunotherapy (AIT). Alum triggers the release of neutrophil extracellular traps (NETs) by neutrophils. NETs contain expelled decondensed chromatin associated with granular materi...
Autores principales: | Karacs, Jasmine, Reithofer, Manuel, Kitzmüller, Claudia, Kraller, Markus, Schmalz, Stefanie, Bleichert, Sonja, Huppa, Johannes B., Stockinger, Hannes, Bohle, Barbara, Jahn-Schmid, Beatrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066953/ https://www.ncbi.nlm.nih.gov/pubmed/33915724 http://dx.doi.org/10.3390/vaccines9040321 |
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