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Pancreatic Cancer Signaling Pathways, Genetic Alterations, and Tumor Microenvironment: The Barriers Affecting the Method of Treatment

Genetic alterations, especially the K-Ras mutation, carry the heaviest burden in the progression of pancreatic precursor lesions into pancreatic ductal adenocarcinoma (PDAC). The tumor microenvironment is one of the challenges that hinder the therapeutic approaches from functioning sufficiently and...

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Detalles Bibliográficos
Autores principales:	Javadrashid, Darya, Baghbanzadeh, Amir, Derakhshani, Afshin, Leone, Patrizia, Silvestris, Nicola, Racanelli, Vito, Solimando, Antonio Giovanni, Baradaran, Behzad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067185/ https://www.ncbi.nlm.nih.gov/pubmed/33918146 http://dx.doi.org/10.3390/biomedicines9040373

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