Previous Humoral Immunity to the Endemic Seasonal Alphacoronaviruses NL63 and 229E Is Associated with Worse Clinical Outcome in COVID-19 and Suggests Original Antigenic Sin

Antibody-dependent enhancement (ADE) of severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) infection has been hypothesized. However, to date, there has been no in vitro or in vivo evidence supporting this. Cross-reactivity exists between SARS CoV-2 and other Coronaviridae for both cellular...

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Detalles Bibliográficos
Autores principales: Focosi, Daniele, Genoni, Angelo, Lucenteforte, Ersilia, Tillati, Silvia, Tamborini, Antonio, Spezia, Pietro Giorgio, Azzi, Lorenzo, Baj, Andreina, Maggi, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067214/
https://www.ncbi.nlm.nih.gov/pubmed/33915711
http://dx.doi.org/10.3390/life11040298

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