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Phosphatidylinositol Stabilizes Fluid-Phase Liposomes Loaded with a Melphalan Lipophilic Prodrug
Previously, a liposomal formulation of a chemotherapeutic agent melphalan (Mlph) incorporated in a fluid lipid bilayer of natural phospholipids in the form of dioleoylglyceride ester (MlphDG) was developed and the antitumor effect was confirmed in mouse models. The formulation composed of egg phosph...
Autores principales: | Tretiakova, Daria, Le-Deigen, Irina, Onishchenko, Natalia, Kuntsche, Judith, Kudryashova, Elena, Vodovozova, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067299/ https://www.ncbi.nlm.nih.gov/pubmed/33915726 http://dx.doi.org/10.3390/pharmaceutics13040473 |
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