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Experimental Evidence of Generation and Reception by a Transluminal Axisymmetric Shear Wave Elastography Prototype

Experimental evidence on testing a non-ultrasonic-based probe for a new approach in transluminal elastography was presented. The proposed modality generated shear waves by inducing oscillatory rotation on the lumen wall. Detection of the propagated waves was achieved at a set of receivers in mechani...

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Autores principales: Gomez, Antonio, Hurtado, Manuel, Callejas, Antonio, Torres, Jorge, Saffari, Nader, Rus, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067333/
https://www.ncbi.nlm.nih.gov/pubmed/33918357
http://dx.doi.org/10.3390/diagnostics11040645
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author Gomez, Antonio
Hurtado, Manuel
Callejas, Antonio
Torres, Jorge
Saffari, Nader
Rus, Guillermo
author_facet Gomez, Antonio
Hurtado, Manuel
Callejas, Antonio
Torres, Jorge
Saffari, Nader
Rus, Guillermo
author_sort Gomez, Antonio
collection PubMed
description Experimental evidence on testing a non-ultrasonic-based probe for a new approach in transluminal elastography was presented. The proposed modality generated shear waves by inducing oscillatory rotation on the lumen wall. Detection of the propagated waves was achieved at a set of receivers in mechanical contact with the lumen wall. The excitation element of the probe was an electromagnetic rotational actuator whilst the sensing element was comprised by a uniform anglewise arrangement of four piezoelectric receivers. The prototype was tested in two soft-tissue-mimicking phantoms that contained lumenlike conduits and stiffer inclusions. The shear wave speed of the different components of the phantoms was characterized using shear wave elastography. These values were used to estimate the time-of-flight of the expected reflections. Ultrafast ultrasound imaging, based on Loupas’ algorithm, was used to estimate the displacement field in transversal planes to the lumenlike conduit and to compare against the readouts from the transluminal transmission–reception tests. Experimental observations between ultrafast imaging and the transluminal probe were in good agreement, and reflections due to the stiffer inclusions were detected by the transluminal probe. The obtained experimental evidence provided proof-of-concept for the transluminal elastography probe and encouraged further exploration of clinical applications.
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spelling pubmed-80673332021-04-25 Experimental Evidence of Generation and Reception by a Transluminal Axisymmetric Shear Wave Elastography Prototype Gomez, Antonio Hurtado, Manuel Callejas, Antonio Torres, Jorge Saffari, Nader Rus, Guillermo Diagnostics (Basel) Article Experimental evidence on testing a non-ultrasonic-based probe for a new approach in transluminal elastography was presented. The proposed modality generated shear waves by inducing oscillatory rotation on the lumen wall. Detection of the propagated waves was achieved at a set of receivers in mechanical contact with the lumen wall. The excitation element of the probe was an electromagnetic rotational actuator whilst the sensing element was comprised by a uniform anglewise arrangement of four piezoelectric receivers. The prototype was tested in two soft-tissue-mimicking phantoms that contained lumenlike conduits and stiffer inclusions. The shear wave speed of the different components of the phantoms was characterized using shear wave elastography. These values were used to estimate the time-of-flight of the expected reflections. Ultrafast ultrasound imaging, based on Loupas’ algorithm, was used to estimate the displacement field in transversal planes to the lumenlike conduit and to compare against the readouts from the transluminal transmission–reception tests. Experimental observations between ultrafast imaging and the transluminal probe were in good agreement, and reflections due to the stiffer inclusions were detected by the transluminal probe. The obtained experimental evidence provided proof-of-concept for the transluminal elastography probe and encouraged further exploration of clinical applications. MDPI 2021-04-02 /pmc/articles/PMC8067333/ /pubmed/33918357 http://dx.doi.org/10.3390/diagnostics11040645 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gomez, Antonio
Hurtado, Manuel
Callejas, Antonio
Torres, Jorge
Saffari, Nader
Rus, Guillermo
Experimental Evidence of Generation and Reception by a Transluminal Axisymmetric Shear Wave Elastography Prototype
title Experimental Evidence of Generation and Reception by a Transluminal Axisymmetric Shear Wave Elastography Prototype
title_full Experimental Evidence of Generation and Reception by a Transluminal Axisymmetric Shear Wave Elastography Prototype
title_fullStr Experimental Evidence of Generation and Reception by a Transluminal Axisymmetric Shear Wave Elastography Prototype
title_full_unstemmed Experimental Evidence of Generation and Reception by a Transluminal Axisymmetric Shear Wave Elastography Prototype
title_short Experimental Evidence of Generation and Reception by a Transluminal Axisymmetric Shear Wave Elastography Prototype
title_sort experimental evidence of generation and reception by a transluminal axisymmetric shear wave elastography prototype
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067333/
https://www.ncbi.nlm.nih.gov/pubmed/33918357
http://dx.doi.org/10.3390/diagnostics11040645
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