Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto’s Thyroiditis

In Hashimoto’s thyroiditis (HT), oxidative stress (OS) is driven by Th1 cytokines’ response interfering with the normal function of thyrocytes. OS results from an imbalance between an excessive production of reactive oxygen species (ROS) and a lowering of antioxidant production. Moreover, OS has bee...

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Detalles Bibliográficos
Autores principales: Hepp, Michaël, Werion, Alexis, De Greef, Axel, de Ville de Goyet, Christine, de Bournonville, Marc, Behets, Catherine, Lengelé, Benoit, Daumerie, Chantal, Mourad, Michel, Ludgate, Marian, Many, Marie-Christine, Joris, Virginie, Craps, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067526/
https://www.ncbi.nlm.nih.gov/pubmed/33916948
http://dx.doi.org/10.3390/ijms22083806

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