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A Bit Stickier, a Bit Slower, a Lot Stiffer: Specific vs. Nonspecific Binding of Gal4 to DNA

Transcription factors regulate gene activity by binding specific regions of genomic DNA thanks to a subtle interplay of specific and nonspecific interactions that is challenging to quantify. Here, we exploit Reflective Phantom Interface (RPI), a label-free biosensor based on optical reflectivity, to...

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Detalles Bibliográficos
Autores principales: Carzaniga, Thomas, Zanchetta, Giuliano, Frezza, Elisa, Casiraghi, Luca, Vanjur, Luka, Nava, Giovanni, Tagliabue, Giovanni, Dieci, Giorgio, Buscaglia, Marco, Bellini, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067546/
https://www.ncbi.nlm.nih.gov/pubmed/33916983
http://dx.doi.org/10.3390/ijms22083813