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A Bit Stickier, a Bit Slower, a Lot Stiffer: Specific vs. Nonspecific Binding of Gal4 to DNA
Transcription factors regulate gene activity by binding specific regions of genomic DNA thanks to a subtle interplay of specific and nonspecific interactions that is challenging to quantify. Here, we exploit Reflective Phantom Interface (RPI), a label-free biosensor based on optical reflectivity, to...
Autores principales: | Carzaniga, Thomas, Zanchetta, Giuliano, Frezza, Elisa, Casiraghi, Luca, Vanjur, Luka, Nava, Giovanni, Tagliabue, Giovanni, Dieci, Giorgio, Buscaglia, Marco, Bellini, Tommaso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067546/ https://www.ncbi.nlm.nih.gov/pubmed/33916983 http://dx.doi.org/10.3390/ijms22083813 |
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