BH3 Mimetic Sensitivity of Colorectal Cancer Cell Lines in Correlation with Molecular Features Identifies Predictors of Response

Colorectal cancer (CRC) is a heterogeneous disease, which in part explains the differential response to chemotherapy observed in the clinic. BH3 mimetics, which target anti-apoptotic BCL-2 family members, have shown potential in the treatment of hematological malignancies and offer promise for the t...

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Detalles Bibliográficos
Autores principales: Zhang, Le, Ramesh, Prashanthi, Steinmetz, Maxime, Medema, Jan Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067732/
https://www.ncbi.nlm.nih.gov/pubmed/33917026
http://dx.doi.org/10.3390/ijms22083811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067732/
https://www.ncbi.nlm.nih.gov/pubmed/33917026
http://dx.doi.org/10.3390/ijms22083811

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