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BH3 Mimetic Sensitivity of Colorectal Cancer Cell Lines in Correlation with Molecular Features Identifies Predictors of Response
Colorectal cancer (CRC) is a heterogeneous disease, which in part explains the differential response to chemotherapy observed in the clinic. BH3 mimetics, which target anti-apoptotic BCL-2 family members, have shown potential in the treatment of hematological malignancies and offer promise for the t...
Autores principales: | Zhang, Le, Ramesh, Prashanthi, Steinmetz, Maxime, Medema, Jan Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067732/ https://www.ncbi.nlm.nih.gov/pubmed/33917026 http://dx.doi.org/10.3390/ijms22083811 |
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