Zona Pellucida Protein 2 (ZP2) Is Expressed in Colon Cancer and Promotes Cell Proliferation

SIMPLE SUMMARY: Our study shows ZP2 to be a new biomarker for diagnosis, best used in combination with other low abundant genes in colon cancer. Furthermore, ZP2 promotes cell proliferation via the ERK1/2-cyclinD1-signaling pathway. We demonstrate that ZP2 mRNA is expressed in a low-abundant manner...

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Detalles Bibliográficos
Autores principales: Kraus, Dominik, Glassmann, Alexander, Golletz, Carsten, Kristiansen, Glen, Winter, Jochen, Probstmeier, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067760/
https://www.ncbi.nlm.nih.gov/pubmed/33917056
http://dx.doi.org/10.3390/cancers13081759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067760/
https://www.ncbi.nlm.nih.gov/pubmed/33917056
http://dx.doi.org/10.3390/cancers13081759

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