Determination of Antiviral Drugs and Their Metabolites Using Micro-Solid Phase Extraction and UHPLC-MS/MS in Reversed-Phase and Hydrophilic Interaction Chromatography Modes

Two new ultra-high performance liquid chromatography (UHPLC) methods for analyzing 21 selected antivirals and their metabolites were optimized, including sample preparation step, LC separation conditions, and tandem mass spectrometry detection. Micro-solid phase extraction in pipette tips was used t...

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Detalles Bibliográficos
Autores principales: Fical, Luboš, Khalikova, Maria, Kočová Vlčková, Hana, Lhotská, Ivona, Hadysová, Zuzana, Vokřál, Ivan, Červený, Lukáš, Švec, František, Nováková, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067820/
https://www.ncbi.nlm.nih.gov/pubmed/33917128
http://dx.doi.org/10.3390/molecules26082123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067820/
https://www.ncbi.nlm.nih.gov/pubmed/33917128
http://dx.doi.org/10.3390/molecules26082123

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