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Glycan-Induced Protein Dynamics in Human Norovirus P Dimers Depend on Virus Strain and Deamidation Status

Noroviruses are the major cause of viral gastroenteritis and re-emerge worldwide every year, with GII.4 currently being the most frequent human genotype. The norovirus capsid protein VP1 is essential for host immune response. The P domain mediates cell attachment via histo blood-group antigens (HBGA...

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Detalles Bibliográficos
Autores principales: Dülfer, Jasmin, Yan, Hao, Brodmerkel, Maxim N., Creutznacher, Robert, Mallagaray, Alvaro, Peters, Thomas, Caleman, Carl, Marklund, Erik G., Uetrecht, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067865/
https://www.ncbi.nlm.nih.gov/pubmed/33917179
http://dx.doi.org/10.3390/molecules26082125