Modeling protein-protein interactions in axon initial segment to understand their potential impact on action potential initiation

The axon initial segment (AIS) region is crucial for action potential initiation due to the presence of high-density AIS protein voltage-gated sodium channels (Na(v)). Na(v) channels comprise several serine residues responsible for the recruitment of Na(v) channels into the structure of AIS through...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Piyush, Kulasiri, Don, Samarasinghe, Sandhya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067952/
https://www.ncbi.nlm.nih.gov/pubmed/33063731
http://dx.doi.org/10.4103/1673-5374.295332

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