Prevention of Bone Destruction by Mechanical Loading Is Not Enhanced by the Bruton’s Tyrosine Kinase Inhibitor CC-292 in Myeloma Bone Disease

Limiting bone resorption and regenerating bone tissue are treatment goals in myeloma bone disease (MMBD). Physical stimuli such as mechanical loading prevent bone destruction and enhance bone mass in the MOPC315.BM.Luc model of MMBD. It is unknown whether treatment with the Bruton’s tyrosine kinase...

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Detalles Bibliográficos
Autores principales: Ziouti, Fani, Rummler, Maximilian, Steyn, Beatrice, Thiele, Tobias, Seliger, Anne, Duda, Georg N., Bogen, Bjarne, Willie, Bettina M., Jundt, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067978/
https://www.ncbi.nlm.nih.gov/pubmed/33917250
http://dx.doi.org/10.3390/ijms22083840

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