(13)C Metabolic Flux Analysis Indicates Endothelial Cells Attenuate Metabolic Perturbations by Modulating TCA Activity

Disrupted endothelial metabolism is linked to endothelial dysfunction and cardiovascular disease. Targeted metabolic inhibitors are potential therapeutics; however, their systemic impact on endothelial metabolism remains unknown. In this study, we combined stable isotope labeling with (13)C metaboli...

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Detalles Bibliográficos
Autores principales: Moiz, Bilal, Garcia, Jonathan, Basehore, Sarah, Sun, Angela, Li, Andrew, Padmanabhan, Surya, Albus, Kaitlyn, Jang, Cholsoon, Sriram, Ganesh, Clyne, Alisa Morss
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068087/
https://www.ncbi.nlm.nih.gov/pubmed/33917224
http://dx.doi.org/10.3390/metabo11040226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068087/
https://www.ncbi.nlm.nih.gov/pubmed/33917224
http://dx.doi.org/10.3390/metabo11040226

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