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(13)C Metabolic Flux Analysis Indicates Endothelial Cells Attenuate Metabolic Perturbations by Modulating TCA Activity
Disrupted endothelial metabolism is linked to endothelial dysfunction and cardiovascular disease. Targeted metabolic inhibitors are potential therapeutics; however, their systemic impact on endothelial metabolism remains unknown. In this study, we combined stable isotope labeling with (13)C metaboli...
Autores principales: | Moiz, Bilal, Garcia, Jonathan, Basehore, Sarah, Sun, Angela, Li, Andrew, Padmanabhan, Surya, Albus, Kaitlyn, Jang, Cholsoon, Sriram, Ganesh, Clyne, Alisa Morss |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068087/ https://www.ncbi.nlm.nih.gov/pubmed/33917224 http://dx.doi.org/10.3390/metabo11040226 |
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