Cargando…

Novel Ring Systems: Spiro[Cycloalkane] Derivatives of Triazolo- and Tetrazolo-Pyridazines

In orderto synthesize new pyridazine derivatives anellated with different nitrogen heterocyclic moieties, spiro[cycloalkane]pyridazinones were transformed into the corresponding thioxo derivatives via a reaction with phosphorus pentasulfide. The reaction of the formed 2,3-diazaspiro[5.5]undec-3-ene-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sepsey Für, Csilla, Riszter, Gergő, SzigetvárI, Áron, Dékány, Miklós, Keglevich, György, HazaI, László, BölcskeI, Hedvig
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068119/ https://www.ncbi.nlm.nih.gov/pubmed/33917797 http://dx.doi.org/10.3390/molecules26082140

Ejemplares similares

Attempted Synthesis of Vinca Alkaloids Condensed with Three-Membered Rings
por: Keglevich, András, et al.
Publicado: (2018)

Synthesis and In Vitro Anticancer Evaluation of Novel Chrysin and 7-Aminochrysin Derivatives
por: Mayer, Szabolcs, et al.
Publicado: (2020)

Synthesis and Cytotoxic Activity of New Vindoline Derivatives Coupled to Natural and Synthetic Pharmacophores
por: Keglevich, András, et al.
Publicado: (2020)

Biomimetic synthesis and HPLC–ECD analysis of the isomers of dracocephins A and B
por: Ilkei, Viktor, et al.
Publicado: (2016)

Synthesis and quantitative structure–activity relationship study of substituted imidazophosphor ester based tetrazolo[1,5-b]pyridazines as antinociceptive/anti-inflammatory agents
por: Abdou, Wafaa M, et al.
Publicado: (2013)

A multicomponent tetrazolo indole synthesis
por: Lei, Xiaofang, et al.
Publicado: (2021)

6-Chloro-3-(3-methylphenyl)-1,2,4-triazolo[4,3-b]pyridazine
por: Preis, Jasmin, et al.
Publicado: (2011)

Discovery of Triazolo-pyridazine/-pyrimidine Derivatives Bearing Aromatic (Heterocycle)-Coupled Azole Units as Class II c-Met Inhibitors
por: Zhang, Qian, et al.
Publicado: (2020)

Radical cation Diels–Alder reactions of arylidene cycloalkanes
por: Nakayama, Kaii, et al.
Publicado: (2022)

Fluorination of some highly functionalized cycloalkanes: chemoselectivity and substrate dependence
por: Remete, Attila Márió, et al.
Publicado: (2017)

Three component synthesis of triazolo[1,2-a]indazole-trione and spiro triazolo[1,2-a]indazole-tetraones using GO/SiO(2)/Co (II)
por: Mirheidari, Mahnaz, et al.
Publicado: (2022)

Crystal structure of [1,2,4] triazolo[4,3- b ]pyridazine derivatives as BRD4 bromodomain inhibitors and structure–activity relationship study
por: Kim, Jung-Hoon, et al.
Publicado: (2023)

Modifications on the Basic Skeletons of Vinblastine and Vincristine
por: Keglevich, Péter, et al.
Publicado: (2012)

Synthesis and biological evaluation of the new ring system benzo[f]pyrimido[1,2-d][1,2,3]triazolo[1,5-a][1,4]diazepine and its cycloalkane and cycloalkene condensed analogues
por: El Haimer, Mohamed, et al.
Publicado: (2021)

A review of technology giants’ healthcare collaborations
por: Szigetvári, Gergő, et al.
Publicado: (2023)

Synthesis of 4-(Phenylchalcogenyl)tetrazolo[1,5-a]quinolines by Bicyclization of 2-Azidobenzaldehydes with Phenylchalcogenylacetonitrile
por: Monzon, Loana I., et al.
Publicado: (2023)

Optimization and a Kinetic Study on the Acidic Hydrolysis of Dialkyl α-Hydroxybenzylphosphonates
por: Harsági, Nikoletta, et al.
Publicado: (2020)

Production of renewable long-chained cycloalkanes from biomass-derived furfurals and cyclic ketones
por: Liu, Qiying, et al.
Publicado: (2018)

Design and Evaluation of Novel Antimicrobial and Anticancer Agents Among Tetrazolo[1,5-c]quinazoline-5-thione S-Derivatives
por: Antypenko, Lyudmyla M., et al.
Publicado: (2013)

Synthesis and Anti-Proliferative Assessment of Triazolo-Thiadiazepine and Triazolo-Thiadiazine Scaffolds
por: Boraei, Ahmed T. A., et al.
Publicado: (2019)

Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process
por: Zhao, Jiancan, et al.
Publicado: (2013)

Synthesis of jet fuel range branched cycloalkanes with mesityl oxide and 2-methylfuran from lignocellulose
por: Li, Shanshan, et al.
Publicado: (2016)

Hollow MFI Zeolite Supported Pt Catalysts for Highly Selective and Stable Hydrodeoxygenation of Guaiacol to Cycloalkanes
por: Niu, Xiaopo, et al.
Publicado: (2019)

Three host peculiarities of a cycloalkane-based micelle toward large metal-complex guests
por: Hanafusa, Mamiko, et al.
Publicado: (2020)

QSPR Models to Predict Thermodynamic Properties of Cycloalkanes  Using Molecular Descriptors and GA-MLR Method
por: Joudaki, Daryoush, et al.
Publicado: (2020)

Cycloalkane-modified amphiphilic polymers provide direct extraction of membrane proteins for CryoEM analysis
por: Higgins, Anna J., et al.
Publicado: (2021)

Synthesis of Some New Pyridazine Derivatives for Anti-HAV Evaluation
por: Flefel, Eman M., et al.
Publicado: (2017)

Annellation of Triazole and Tetrazole Systems onto Pyrrolo[2,3-d]pyrimidines: Synthesis of Tetrazolo[1,5-c]-pyrrolo[3,2-e]-pyrimidines and Triazolo[1,5-c]pyrrolo-[3,2-e]pyrimidines as Potential Antibacterial Agents
por: Dave, Chaitanya G., et al.
Publicado: (2002)

A comparison of hydrogen release kinetics from 5- and 6-membered 1,2-BN-cycloalkanes
por: Giustra, Zachary X., et al.
Publicado: (2021)

Tetrakis(pyridazine-κN)bis(thiocyanato-κN)nickel(II) pyridazine disolvate
por: Wöhlert, Susanne, et al.
Publicado: (2012)

Tetrakis(pyridazine-κN)bis(selenocyanato-κN)cobalt(II) pyridazine disolvate
por: Wöhlert, Susanne, et al.
Publicado: (2012)

Tetrakis(pyridazine-κN)bis(selenocyanato-κN)nickel(II) pyridazine disolvate
por: Wöhlert, Susanne, et al.
Publicado: (2012)

Polyfunctional Nitriles in Organic Syntheses: A Novel Route to Aminopyrroles, Pyridazines and Pyrazolo[3,4-c]pyridazines
por: Al-Mousawi, Saleh M., et al.
Publicado: (2009)

Synthesis, effect of substituents on the regiochemistry and equilibrium studies of tetrazolo[1,5-a]pyrimidine/2-azidopyrimidines
por: Scapin, Elisandra, et al.
Publicado: (2017)

Synthesis of Spirooxindole-O-Naphthoquinone-Tetrazolo[1,5-a]Pyrimidine Hybrids as Potential Anticancer Agents
por: Wu, Liqiang, et al.
Publicado: (2018)

One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia
por: Wang, Fei, et al.
Publicado: (2020)

Dehydrogenation of Cycloalkanes over N-Doped Carbon-Supported Catalysts: The Effects of Active Component and Molecular Structure of the Substrate
por: Wang, Jian, et al.
Publicado: (2021)

Author Correction: Cycloalkane-modified amphiphilic polymers provide direct extraction of membrane proteins for CryoEM analysis
por: Higgins, Anna J., et al.
Publicado: (2022)

Synthesis and In Vitro Anticancer Evaluation of Flavone—1,2,3-Triazole Hybrids
por: Németh-Rieder, Alexandra, et al.
Publicado: (2023)

4-Carboxypyridazin-1-ium chloride
por: Starosta, Wojciech, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_p5vouteheokal6garvnov7kqm2