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Arthrobacter woluwensis Bacteremia: A Clinical and Genomic Report

Arthrobacter woluwensis is a Gram-positive, aerobic Actinobacteria that is widely distributed in the environment worldwide. Little is known about A. woluwensis infection and it is commonly mis-identified by culturing with commercial kits. To date, only six cases of bacteremia caused by A. woluwensis...

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Autores principales: Li, Shu-Yuan, Kao, Chin-Chuan, Hu, Yu-Cheng, Lai, Chung-Hsu, Jiang, Yi-Ping, Mao, Yan-Chiao, Huang, Yao-Ting, Liu, Po-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068144/
https://www.ncbi.nlm.nih.gov/pubmed/33917709
http://dx.doi.org/10.3390/pathogens10040443
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author Li, Shu-Yuan
Kao, Chin-Chuan
Hu, Yu-Cheng
Lai, Chung-Hsu
Jiang, Yi-Ping
Mao, Yan-Chiao
Huang, Yao-Ting
Liu, Po-Yu
author_facet Li, Shu-Yuan
Kao, Chin-Chuan
Hu, Yu-Cheng
Lai, Chung-Hsu
Jiang, Yi-Ping
Mao, Yan-Chiao
Huang, Yao-Ting
Liu, Po-Yu
author_sort Li, Shu-Yuan
collection PubMed
description Arthrobacter woluwensis is a Gram-positive, aerobic Actinobacteria that is widely distributed in the environment worldwide. Little is known about A. woluwensis infection and it is commonly mis-identified by culturing with commercial kits. To date, only six cases of bacteremia caused by A. woluwensis have been reported in the literature. Herein, we report a case of Arthrobacter woluwensis bacteremia in an immunocompromised host. In this case report, the results of antimicrobial susceptibility testing showed that this clinical isolate of A. woluwensis is sensitive to vancomycin, teicoplanin, but resistant to penicillin, cephalosporin and ciprofloxacin. Additionally, whole genome sequencing analysis identified common subunits of the urease system.
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spelling pubmed-80681442021-04-25 Arthrobacter woluwensis Bacteremia: A Clinical and Genomic Report Li, Shu-Yuan Kao, Chin-Chuan Hu, Yu-Cheng Lai, Chung-Hsu Jiang, Yi-Ping Mao, Yan-Chiao Huang, Yao-Ting Liu, Po-Yu Pathogens Article Arthrobacter woluwensis is a Gram-positive, aerobic Actinobacteria that is widely distributed in the environment worldwide. Little is known about A. woluwensis infection and it is commonly mis-identified by culturing with commercial kits. To date, only six cases of bacteremia caused by A. woluwensis have been reported in the literature. Herein, we report a case of Arthrobacter woluwensis bacteremia in an immunocompromised host. In this case report, the results of antimicrobial susceptibility testing showed that this clinical isolate of A. woluwensis is sensitive to vancomycin, teicoplanin, but resistant to penicillin, cephalosporin and ciprofloxacin. Additionally, whole genome sequencing analysis identified common subunits of the urease system. MDPI 2021-04-08 /pmc/articles/PMC8068144/ /pubmed/33917709 http://dx.doi.org/10.3390/pathogens10040443 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Li, Shu-Yuan
Kao, Chin-Chuan
Hu, Yu-Cheng
Lai, Chung-Hsu
Jiang, Yi-Ping
Mao, Yan-Chiao
Huang, Yao-Ting
Liu, Po-Yu
Arthrobacter woluwensis Bacteremia: A Clinical and Genomic Report
title Arthrobacter woluwensis Bacteremia: A Clinical and Genomic Report
title_full Arthrobacter woluwensis Bacteremia: A Clinical and Genomic Report
title_fullStr Arthrobacter woluwensis Bacteremia: A Clinical and Genomic Report
title_full_unstemmed Arthrobacter woluwensis Bacteremia: A Clinical and Genomic Report
title_short Arthrobacter woluwensis Bacteremia: A Clinical and Genomic Report
title_sort arthrobacter woluwensis bacteremia: a clinical and genomic report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068144/
https://www.ncbi.nlm.nih.gov/pubmed/33917709
http://dx.doi.org/10.3390/pathogens10040443
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