Acetyl-CoA Metabolism and Histone Acetylation in the Regulation of Aging and Lifespan

Acetyl-CoA is a metabolite at the crossroads of central metabolism and the substrate of histone acetyltransferases regulating gene expression. In many tissues fasting or lifespan extending calorie restriction (CR) decreases glucose-derived metabolic flux through ATP-citrate lyase (ACLY) to reduce cy...

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Detalles Bibliográficos
Autor principal: Bradshaw, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068152/
https://www.ncbi.nlm.nih.gov/pubmed/33917812
http://dx.doi.org/10.3390/antiox10040572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068152/
https://www.ncbi.nlm.nih.gov/pubmed/33917812
http://dx.doi.org/10.3390/antiox10040572

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