A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition

Inflammasome targeting and controlling dysbiosis are promising therapeutic approaches to control ulcerative colitis. This report is the first to investigate the mechanisms underlying the coloprotective effects of rosuvastatin and Lactobacillus and their combined therapy on dextran sodium sulfate (DS...

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Detalles Bibliográficos
Autores principales: Saber, Sameh, Abd El-Fattah, Eslam E., Yahya, Galal, Gobba, Naglaa A., Maghmomeh, Abdalkareem Omar, Khodir, Ahmed E., Mourad, Ahmed A. E., Saad, Ahmed S., Mohammed, Hager G., Nouh, Nehal A., Shata, Ahmed, Amin, Noha A., Abou El-Rous, Magdy, Girgis, Samuel, El-Ahwany, Eman, Khalaf, Eman M., El-Kott, Attalla F., El-Baz, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068273/
https://www.ncbi.nlm.nih.gov/pubmed/33917884
http://dx.doi.org/10.3390/ph14040341

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