Naphthalimide-Containing BP100 Leads to Higher Model Membranes Interactions and Antimicrobial Activity

In a large variety of organisms, antimicrobial peptides (AMPs) are primary defenses against pathogens. BP100 (KKLFKKILKYL-NH(2)), a short, synthetic, cationic AMP, is active against bacteria and displays low toxicity towards eukaryotic cells. BP100 acquires a α-helical conformation upon interaction...

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Detalles Bibliográficos
Autores principales: Carretero, Gustavo Penteado Battesini, Saraiva, Greice Kelle Viegas, Rodrigues, Magali Aparecida, Kiyota, Sumika, Bemquerer, Marcelo Porto, Chaimovich, Hernan, Cuccovia, Iolanda Midea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068292/
https://www.ncbi.nlm.nih.gov/pubmed/33917850
http://dx.doi.org/10.3390/biom11040542

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