Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection

Acute disseminated encephalomyelitis (ADEM) is an inflammatory, demyelinating, and rapidly progressive disorder of the central nervous system. This condition is also known as postinfectious encephalomyelitis, and it is characterized by multifocal lesions in the brain and spinal cord with widespread...

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Autores principales: Kacmaz, Ebru, Bozan, Gurkan, Carman, Kursat Bora, Kilic, Omer, Arslanoglu, Mehmet Ozgur, Toprak, Ugur, Kavaz Tufan, Aslı, Yarar, Coskun, Dinleyici, Ener Cagri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068525/
https://www.ncbi.nlm.nih.gov/pubmed/33954003
http://dx.doi.org/10.1155/2021/5570566
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author Kacmaz, Ebru
Bozan, Gurkan
Carman, Kursat Bora
Kilic, Omer
Arslanoglu, Mehmet Ozgur
Toprak, Ugur
Kavaz Tufan, Aslı
Yarar, Coskun
Dinleyici, Ener Cagri
author_facet Kacmaz, Ebru
Bozan, Gurkan
Carman, Kursat Bora
Kilic, Omer
Arslanoglu, Mehmet Ozgur
Toprak, Ugur
Kavaz Tufan, Aslı
Yarar, Coskun
Dinleyici, Ener Cagri
author_sort Kacmaz, Ebru
collection PubMed
description Acute disseminated encephalomyelitis (ADEM) is an inflammatory, demyelinating, and rapidly progressive disorder of the central nervous system. This condition is also known as postinfectious encephalomyelitis, and it is characterized by multifocal lesions in the brain and spinal cord with widespread neurological findings. High doses of intravenous (IV) methylprednisolone, intravenous immunoglobulin (IVIG), and plasma exchange (PLEX) treatments comprise the first-line therapy. There are limited pediatric case reports refractory to standard treatment. Here, we present the case of a 17-year-old girl diagnosed with ADEM associated with Salmonella infection, which was treated with rituximab.
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spelling pubmed-80685252021-05-04 Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection Kacmaz, Ebru Bozan, Gurkan Carman, Kursat Bora Kilic, Omer Arslanoglu, Mehmet Ozgur Toprak, Ugur Kavaz Tufan, Aslı Yarar, Coskun Dinleyici, Ener Cagri Case Rep Pediatr Case Report Acute disseminated encephalomyelitis (ADEM) is an inflammatory, demyelinating, and rapidly progressive disorder of the central nervous system. This condition is also known as postinfectious encephalomyelitis, and it is characterized by multifocal lesions in the brain and spinal cord with widespread neurological findings. High doses of intravenous (IV) methylprednisolone, intravenous immunoglobulin (IVIG), and plasma exchange (PLEX) treatments comprise the first-line therapy. There are limited pediatric case reports refractory to standard treatment. Here, we present the case of a 17-year-old girl diagnosed with ADEM associated with Salmonella infection, which was treated with rituximab. Hindawi 2021-04-17 /pmc/articles/PMC8068525/ /pubmed/33954003 http://dx.doi.org/10.1155/2021/5570566 Text en Copyright © 2021 Ebru Kacmaz et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kacmaz, Ebru
Bozan, Gurkan
Carman, Kursat Bora
Kilic, Omer
Arslanoglu, Mehmet Ozgur
Toprak, Ugur
Kavaz Tufan, Aslı
Yarar, Coskun
Dinleyici, Ener Cagri
Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection
title Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection
title_full Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection
title_fullStr Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection
title_full_unstemmed Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection
title_short Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection
title_sort rituximab treatment in acute disseminated encephalomyelitis associated with salmonella infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068525/
https://www.ncbi.nlm.nih.gov/pubmed/33954003
http://dx.doi.org/10.1155/2021/5570566
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