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Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma
Background Precision medicine and drug repurposing are attractive strategies, especially for tumors with worse prognosis. Glioblastoma is a highly malignant brain tumor with limited treatment options and short survival times. We identified novel BRAF (47-438del) and PIK3R1 (G376R) mutations in a gli...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068653/ https://www.ncbi.nlm.nih.gov/pubmed/33313992 http://dx.doi.org/10.1007/s10637-020-01037-7 |