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Structural basis of malaria RIFIN binding by LILRB1-containing antibodies

We previously reported that certain Plasmodium falciparum RIFINs, variant surface antigens expressed on infected erythrocytes(1), bind to the inhibitory receptor LAIR1 and insertions of DNA encoding LAIR1 into immunoglobulin genes generate RIFIN-specific antibodies(2,3). To address the general relev...

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Detalles Bibliográficos
Autores principales:	Chen, Yiwei, Xu, Kai, Piccoli, Luca, Foglierini, Mathilde, Tan, Joshua, Jin, Wenjie, Gorman, Jason, Tsybovsky, Yaroslav, Zhang, Baoshan, Traore, Boubacar, Silacci-Fregni, Chiara, Daubenberger, Claudia, Crompton, Peter D., Geiger, Roger, Sallusto, Federica, Kwong, Peter D., Lanzavecchia, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068667/ https://www.ncbi.nlm.nih.gov/pubmed/33790470 http://dx.doi.org/10.1038/s41586-021-03378-6

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