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Higher midlife CAIDE score is associated with increased brain atrophy in a cohort of cognitively healthy middle-aged individuals
BACKGROUND: Structural brain changes associated with Alzheimer’s disease (AD) can occur decades before the onset of symptoms. The Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) score has been suggested to be associated with accelerated brain atrophy in middle-aged subjects but the regional...
Autores principales: | Liu, Xulin, Dounavi, Maria-Eleni, Ritchie, Karen, Wells, Katie, Ritchie, Craig W., Su, Li, Muniz-Terrera, Graciela, O’Brien, John T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068701/ https://www.ncbi.nlm.nih.gov/pubmed/33423129 http://dx.doi.org/10.1007/s00415-020-10383-8 |
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