Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma

Objectives Malignant pleural mesothelioma (MPM) is an occupational disease mainly due to asbestos exposure. Effective therapies for MPM are lacking, making this tumour type a fatal disease. Materials and Methods In order to meet this need and in view of a future “drug repositioning” approach, here w...

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Detalles Bibliográficos
Autores principales: Dell’Anno, Irene, Martin, Sarah A., Barbarino, Marcella, Melani, Alessandra, Silvestri, Roberto, Bottaro, Maria, Paolicchi, Elisa, Corrado, Alda, Cipollini, Monica, Melaiu, Ombretta, Giordano, Antonio, Luzzi, Luca, Gemignani, Federica, Landi, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Preclinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068714/
https://www.ncbi.nlm.nih.gov/pubmed/33300108
http://dx.doi.org/10.1007/s10637-020-01040-y

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