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Broad-Spectrum Antiviral Activity of 3D8, a Nucleic Acid-Hydrolyzing Single-Chain Variable Fragment (scFv), Targeting SARS-CoV-2 and Multiple Coronaviruses In Vitro
The virus behind the current pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the etiology of novel coronavirus disease (COVID-19) and poses a critical public health threat worldwide. Effective therapeutics and vaccines against multiple coronaviruses remain u...
Autores principales: | Lee, Gunsup, Budhathoki, Shailesh, Lee, Geum-Young, Oh, Kwang-ji, Ham, Yeon Kyoung, Kim, Young-Jun, Lim, Ye Rin, Hoang, Phuong Thi, Lee, Yongjun, Lim, Seok-Won, Kim, Jun-Mo, Cho, Seungchan, Kim, Tai-Hyun, Song, Jin-Won, Lee, Sukchan, Kim, Won-Keun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068894/ https://www.ncbi.nlm.nih.gov/pubmed/33918914 http://dx.doi.org/10.3390/v13040650 |
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