Improving Breast Cancer Treatment Specificity Using Aptamers Obtained by 3D Cell-SELEX

Three-dimensional spheroids of non-malignant MCF10A and malignant SKBR3 breast cells were used for subsequent 3D Cell-SELEX to generate aptamers for specific binding and treatment of breast cancer cells. Using 3D Cell-SELEX combined with Next-Generation Sequencing and bioinformatics, ten abundant ap...

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Detalles Bibliográficos
Autores principales: Nelissen, Frank H. T., Peeters, Wenny J. M., Roelofs, Timo P., Nagelkerke, Anika, Span, Paul N., Heus, Hans A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068899/
https://www.ncbi.nlm.nih.gov/pubmed/33918832
http://dx.doi.org/10.3390/ph14040349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068899/
https://www.ncbi.nlm.nih.gov/pubmed/33918832
http://dx.doi.org/10.3390/ph14040349

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