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Improving Breast Cancer Treatment Specificity Using Aptamers Obtained by 3D Cell-SELEX
Three-dimensional spheroids of non-malignant MCF10A and malignant SKBR3 breast cells were used for subsequent 3D Cell-SELEX to generate aptamers for specific binding and treatment of breast cancer cells. Using 3D Cell-SELEX combined with Next-Generation Sequencing and bioinformatics, ten abundant ap...
Autores principales: | Nelissen, Frank H. T., Peeters, Wenny J. M., Roelofs, Timo P., Nagelkerke, Anika, Span, Paul N., Heus, Hans A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068899/ https://www.ncbi.nlm.nih.gov/pubmed/33918832 http://dx.doi.org/10.3390/ph14040349 |
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