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ATP-Dependent Ligases and AEP Primases Affect the Profile and Frequency of Mutations in Mycobacteria under Oxidative Stress

The mycobacterial nonhomologous end-joining pathway (NHEJ) involved in double-strand break (DSB) repair consists of the multifunctional ATP-dependent ligase LigD and the DNA bridging protein Ku. The other ATP-dependent ligases LigC and AEP-primase PrimC are considered as backup in this process. The...

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Detalles Bibliográficos
Autores principales: Brzostek, Anna, Gąsior, Filip, Lach, Jakub, Żukowska, Lidia, Lechowicz, Ewelina, Korycka-Machała, Małgorzata, Strapagiel, Dominik, Dziadek, Jarosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068969/
https://www.ncbi.nlm.nih.gov/pubmed/33918798
http://dx.doi.org/10.3390/genes12040547