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ATP-Dependent Ligases and AEP Primases Affect the Profile and Frequency of Mutations in Mycobacteria under Oxidative Stress
The mycobacterial nonhomologous end-joining pathway (NHEJ) involved in double-strand break (DSB) repair consists of the multifunctional ATP-dependent ligase LigD and the DNA bridging protein Ku. The other ATP-dependent ligases LigC and AEP-primase PrimC are considered as backup in this process. The...
Autores principales: | Brzostek, Anna, Gąsior, Filip, Lach, Jakub, Żukowska, Lidia, Lechowicz, Ewelina, Korycka-Machała, Małgorzata, Strapagiel, Dominik, Dziadek, Jarosław |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068969/ https://www.ncbi.nlm.nih.gov/pubmed/33918798 http://dx.doi.org/10.3390/genes12040547 |
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